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Relevant Publications:

Okada K, Iyer BR, Lammers LG, Gutierrez PA, Li W, Markus SM, McKenney RJ. Conserved roles for the dynein intermediate chain and Ndel1 in assembly and activation of dynein. Nat Commun. 2023 Sep 20;14(1):5833. (Download PDF)

Minckley TF, Dischler AM, Fudge DH, Ghazvini Zadeh E, Li WH, Verhey K, Markus SM, Qin Y. Zn2+ decoration of microtubules arrests axonal transport and displaces tau, doublecortin, and MAP2C. J Cell Biol. 2023 Aug 7;222(8):e202208121.. (Download PDF)

Ton WD, Wang Y, Chai P, Beauchamp-Perez C, Flint NT, Lammers LG, Xiong H, Zhang K, Markus SM. Microtubule binding-induced allostery triggers LIS1 dissociation from dynein prior to cargo transport. Nat Struct Mol Biol. 2023 Jun 15. (Download PDF)

Ide AH, DeLuca KF, Wiggan O, Markus SM*, DeLuca JG*. The role of kinetochore dynein in checkpoint silencing is restricted to disassembly of the corona. Mol Biol Cell. 2023 Jun 1;34(7). *co-corresponding authors. (Download PDF)

Ecklund KH, Marzo MG, Markus SM. Using Budding Yeast as a Model to Understand Dynein-Mediated Cargo Transport. Methods Mol Biol 2023; 2623:25-42. (Download PDF)

Denarier E, Ecklund KH, Berthier G, Favier A, O’Toole ET, Gory-Faure S, De Macedo L, Delphin C, Andrieux A, Markus, SM & Boscheron C. Modeling a disease-correlated tubulin mutation in budding yeast reveals insight into MAP-mediated dynein function. Mol Biol Cell 2021 32. (Download PDF)

Ecklund KH, Bailey ME, Kossen KA, Dietvorst CK, Asbury CL, Markus SM. The microtubule-associated protein She1 coordinates directional spindle positioning by spatially restricting dynein activity. J Cell Sci 2021 Dec 1;134(23). (Download PDF)

Markus SM, Marzo MG, and McKenney RJ. New insights into the mechanism of dynein motor regulation by lissencephaly-1. eLife 2020 9:e59737. (Download PDF)

Marzo MG, Griswold JM, and Markus SM. Pac1/LIS1 promotes an uninhibited conformation of dynein that coordinates its localization and activity. Nat Cell Biol 2020 22, 559-569. (Download PDF)

Marzo MG, Griswold JM, Ruff KN, Buchmeier RE, Fees CP and Markus SM. Molecular basis for dyneinopathies reveals insight into dynein regulation and dysfunction. eLife, Jul 31;8 (2019).

Ecklund KH, Morisaki T, Lammers LG, Marzo MG, Stasevich TJ, and Markus SM. She1 affects dynein through direct interactions with the microtubule and the dynein microtubule-binding domain. Nature Communications, 8, Article number: 2151 (2017). (Download PDF)

Lammers LG and Markus SM. The dynein cortical anchor Num1 activates dynein motility by relieving Pac1/LIS1-mediated inhibition. J Cell Biol. 2015 Oct 26; 211(2): 309-322. (Download PDF) Highlighted in J Cell Biol!

Markus SM, Omer S, Baranowski K, and Lee WL. Improved Plasmids for Fluorescent Protein Tagging of Microtubules in Saccharomyces cerevisiae. Traffic. 2015 Jul; 16(7):773-86. (Download PDF)

Markus SM, Kalutkiewicz KA and Lee WL. Astral microtubule asymmetry provides directional cues for spindle positioning in budding yeast. Exp Cell Res. 2012 Jul; 318(12): 1400-06. (Download PDF)

Markus SM, Kalutkiewicz KA, and Lee WL. She1-mediated inhibition of dynein motility along astral microtubules promotes unidirectional spindle movements. Curr Biol, 2012, 22: 2221-2230. (Download PDF)

Markus SM, Plevock KM, St. Germain BJ, Punch JJ, Meaden CW, Lee WL. Quantitative Analysis of Pac1/LIS1-mediated Dynein Targeting: Implications for Regulation of Dynein Activity in Budding Yeast. Cytoskeleton. 2011 Mar; 68(3): 157-74. (Download PDF)

Markus SM and Lee WL. Regulated Offloading of Cytoplasmic Dynein from Microtubule Plus Ends to the Cortex. Dev Cell. 2011 May; 20(5):639-651. (Download PDF)

Markus SM and Lee WL. Microtubule-dependent Path to the Cell Cortex for Cytoplasmic Dynein in Mitotic Spindle Orientation. Bioarchitecture. 2011 September/October; 1(5): 209-215. (Download PDF)

Markus SM, Punch JJ, Lee WL. Motor and Tail Dependent Targeting of Dynein to Microtubule Plus-Ends and the Cell Cortex. Curr Biol. 2009 Jan; 19(3):196-205. (Download PDF)

Vorvis C, Markus SM, Lee WL. Photoactivatable GFP tagging cassettes for protein-tracking studies in the budding yeast Saccharomyces cerevisiae. Yeast. 2008 Sep; 25(9):651-9. (Download PDF)

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